Glutathione, your body's most abundant intracellular antioxidant, plays a central role in immune regulation. Research shows that glutathione levels decline approximately 10% per decade after age 20, directly impairing lymphocyte function and the body's ability to neutralize free radicals that damage immune cells.
This depletion creates a cascading effect: as glutathione reserves fall, oxidative stress accumulates within immune cells, reducing their capacity to identify and eliminate threats. Natural killer cells and T-lymphocytes become less responsive, leaving the body increasingly vulnerable to infections and slower to recover from illness.
NAD+, another critical coenzyme, declines in parallel with glutathione. NAD+ fuels the metabolic processes that power immune cell activation and repair. When both glutathione and NAD+ are depleted simultaneously, the immune system faces a compounded energy and antioxidant deficit that diet alone often cannot correct.
